Experts around the world – including NJ, NYC and the rest of the Tristate area – are choosing the Leksell Gamma Knife Icon system to treat. OBJECTIVE: The objective of this study is to introduce a new radiosurgical device , the Leksell Gamma Knife Perfexion (Elekta Instruments AB, Stockholm. A new model of Leksell Gamma Knife® (LGK), known as Perfexion™ (LGK PFX), was introduced by Elekta Instrument, AB, Sweden, in This model has a.

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Patient images are then acquired on a MRI or CT scanner and the site of the lesion can be located relative to the frame. As each shot with LGK PFX consists of gamma ray beams coming from eight sectors and each sector has either 4, 8 or 16 mm collimation or complete beam blocking, there are now three possible approaches to the treatment planning: C Sector position which defines a 4 mm collimator.

The LGK PFX demonstrated a high level efficiency in workflow thus reducing significantly the total treatment time especially for the treatment of multiple metastases. The time saved for set-up was proportional to the number of irradiated tumors maximum time saved for set-up was min for a patient with 12 metastases.

National Center for Biotechnology InformationU.

Because of the increased treatment range for the LGK PFX system, the treatment of multiple brain tumors such as brain metastases does not present any difficulty in terms of collision with the collimator system.

The manufacturer’s specification required initial output to be more than 3. On line CBCT imaging will reveal any discrepancy in patient positioning, providing guidance to correct any errors and ensure the treatment accuracy without using the invasive head frame.

Equally high accuracy and ease of use for frame-based or frameless treatments, and for single or multiple targets. Calibration doses used for EBT film ranged from 0 to 8 Gy a total of ten calibration points were obtained.

Sector transition dose was measured to be 0. The 4 and 8 mm collimator sizes are kept the same as for the previous models, but the 14 and 18 mm collimator sizes of the previous models are replaced with a 16 mm collimator size. Icon is specifically designed for intracranial radiosurgery and has unique dosimetrical capabilities. This article is also available for rental through DeepDyve. Such a composite shot allows for optimized dose distribution shape for the individual shots. The adapter is then directly docked to the PPS.


An evaluation of the Model C gamma knife with automatic patient positioning. The system also provides more options to generate plan with high dosimetric conformity. Physical Aspects of Stereotactic Radiosurgery. The created pin prick was then compared with the center of the profile obtained from film analysis. This result was much better than manufacture required specification 0. The PPS provides a more comfortable position for the patient during treatment.

Leksell Gamma Knife® Perfexion™

By continuing to browse the site you are agreeing to our use of cookies. D Sector position which defines a 8 mm collimator. Before exposing the films to radiation, the films were punched with a needle. It furthers the University’s objective of perfexionn in research, scholarship, and education by publishing worldwide. LGK PFX LGK 4C Co sources Co sources Sources move Sources stationary ldksell fixed in position Source-to-focus distance varies from mm to mm Source-to-focus distance fixed at mm 8 moving sectors holding 24 sources each Sources fixed in central radiation unit Collimators fixed – built in the unit Final external collimators interchangeable No collimator helmets Four collimator helmets Collimator sizes: Pathologies previously inaccessible in the head and neck are now treatable due to the increased volume of the radiation cavity.

Appendix A Conformity index CIpaddick conformity index PCI and gradient index GI The indices discussed in this appendix are useful tools to compare competing treatment plans for the same patient.

To purchase short term access, please sign in to your Oxford Academic account above. These qualities enable treatment of larger target volumes, especially close to eloquent areas. Although the design characeristics gqmma LGK PFX are significantly different from those of the previous models, an excellent agreement is seen among 4 mm and 8 mm collimators profiles.

Please see elongated shape of these three shots and blocking pattern of sectors. Accuracy of coincidence of radiological focal point and PPS mechanical isocenter was verified for the 4 mm collimator using the film technique described in the Materials and Methods section.


Design perfexiob performance characteristics are compared with previous models of the gamma knife in a clinical setting. B Detailed view of sectors; each sector holds 24 60 Co sources and can be moved independent of other sectors in desired position to define a collimator size or to block beams. Only three collimator sizes of 4, 8 and 16 mm are now available. Most users bamma sign in with their email address.

Treatment planning of stereotactic convergent gamma-ray irradiation using Co sources. Despite increasing the treatment range, the average source-to-focus distance is still kept very close to previous models due to an improved design of the collimator system of LGK PFX.

Plenum Publishing Corporation; Series of 28 Cases.

Paddick I, Lippitz B. Fully automated treatment delivery allows for small teams and high throughput regardless of treatment volume.

Leksell Gamma Knife® Perfexion™

The concept of giving the prescribed dose to the target volume TV and reducing the dose to the surrounding healthy tissue is objective measure by the quantities known as CI, PCI and GI. Accuracy of co-registration of planning images with Cone Beam CT images.

This model has a radically different design from the earlier models U, B, C and 4C. Each GammaKnife contains about Co radioactive sources that are used to non-invasively deliver a high dose of radiation to treat brain disorders.

A simple dose gradient measurement tool to oerfexion the conformity index. Lower dose to healthy tissue times lower dose to healthy perfexiln and lowest dose to rest of body compared to other SRS modalities 2 2 Ma L, Nichol A, Hossain S, et al.

Fractionated radiation treatment, where a patient receives multiple radiation treatments but lekse,l lower doses thus giving healthy irradiated tissue time to heal between treatments, is a common technique that is used for other radiation therapy devices.

Impact of the model C and Automatic Positioning System on gamma knife radiosurgery: